Interleukin 5, disingkat IL-5 (bahasa Inggris:eosinophil colony-stimulating factor, EDF, TRF) adalah sitokina sekresi sel TH[4] yang berperan dalam perkembangan dan diferensiasi sel B dan eosinofil.[5]
Peningkatan rasio IL-5 dilaporkan terkait dengan asma dan sindrom hipereosinofilik,[5] seperti eosinofilia.[6] Tingginya rasio IL-5 juga ditemukan pada penderita penyakit Graves dan tiroiditis Hashimoto.[7]
Referensi
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000113525 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ (Inggris) "Naive helper T cells from BCG-vaccinated volunteers produce IFN-gamma and IL-5 to mycobacterial antigen-pulsed dendritic cells". Department of Immunology and Infectious Biology, University of Lodz; Kowalewicz-Kulbat M, Kaźmierczak D, Donevski S, Biet F, Pestel J, Rudnicka W. Diakses tanggal 2010-06-08.
- 1 2 (Inggris) "1: IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-06-08.
- ↑ (Inggris) "TARC and IL-5 expression correlates with tissue eosinophilia in peripheral T-cell lymphomas". Department of Pathology, CHU of Liège, University of Liège; Thielen C, Radermacher V, Trimeche M, Roufosse F, Goldman M, Boniver J, de Leval L. Diakses tanggal 2010-06-08.
- ↑ (Inggris) "The role of T-lymphocyte subsets and interleukin-5 blood levels among Indian subjects with autoimmune thyroid disease". Defence Bio-engineering and Electromedical Laboratory; Gopalakrishnan S, Sen S, Adhikari JS, Chugh PK, Sekhri T, Rajan S. Diakses tanggal 2010-06-08.
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