Interleukin 13

Interleukin-13
Struktur yang tersedia PDB Pencarian ortolog: PDBe RCSB Daftar kode ID PDB 1GA3, 1IJZ, 1IK0, 3BPO, 3G6D, 3L5W, 3L5X, 3LB6, 4I77, 4PS4, 5E4E
Pengidentifikasi
Alias	IL13, IL-13, P600, interleukin 13
ID Eksternal	OMIM: 147683; MGI: 96541; HomoloGene: 1649; GeneCards: IL13; OMA:IL13 - orthologs
Pola ekspresi RNA Bgee Manusia Tikus (ortologi) n/a Ekspresi tertinggi di embrio secondary oocyte Zigot seminiferous tubule timus spermatocyte hippocampal formation hippocampus proper bibir spermatid BioGPS Data ekspresi referensi lebih lanjut
Ontologi gen Fungsi molekuler Ikatan protein plasma cytokine receptor binding cytokine activity interleukin-13 receptor binding Komponen seluler sitoplasma external side of plasma membrane extracellular region extracellular space Proses biologis negative regulation of endothelial cell apoptotic process negative regulation of complement-dependent cytotoxicity negative regulation of transforming growth factor beta production positive regulation of lung goblet cell differentiation response to mechanical stimulus response to nicotine positive regulation of release of sequestered calcium ion into cytosol microglial cell activation negative regulation of NAD(P)H oxidase activity cellular response to mechanical stimulus response to lipopolysaccharide negative regulation of lung ciliated cell differentiation positive regulation of ion transport respons imun positive regulation of protein secretion positive regulation of connective tissue growth factor production positive regulation of pancreatic stellate cell proliferation response to ethanol inflammatory response regulation of proton transport positive regulation of smooth muscle cell proliferation negative regulation of neuron death positive regulation of immunoglobulin production positive regulation of B cell proliferation positive regulation of macrophage activation positive regulation of mast cell degranulation cellular response to cytokine stimulus positive regulation of tyrosine phosphorylation of STAT protein regulation of signaling receptor activity cytokine-mediated signaling pathway positive regulation of gene expression positive regulation of cold-induced thermogenesis Sumber:Amigo / QuickGO
Ortologi Spesies Manusia Tikus Entrez 3596 16163 Ensembl ENSG00000169194 ENSMUSG00000020383 UniProt P35225 P20109 RefSeq (mRNA) NM_002188 NM_008355 RefSeq (protein) NP_002179 NP_001341920 NP_001341921 NP_001341922 NP_032381 Location (UCSC) n/a n/a PubMed search [1] [2]
Wikidata
Lihat/Sunting Manusia Lihat/Sunting Tikus

Interleukin 13 (disingkat IL-13) adalah sebuah protein dengan fungsi sitokina yang disekresi berbagai sel, tetapi terutama oleh sel T_H2. Berbagai efek biologis IL-13, seperti halnya IL-4, terkait dengan sebuah faktor transkripsi yaitu STAT6.

Rujukan

Basis data pengawasan otoritas: Nasional	Amerika Serikat Israel

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