| Tahun | Judul | Sebagai | Sutradara | Catatan |
| 1984 | The Wild Life | Penny Harlin | Art Linson | Co-star |
| 1985 | Just One of the Guys | Sandy | Lisa Gottlieb | Co-star |
| Dummies (short film) | | Laurie Frank | |
| 1986 | Thrashin' | Velvet | David Winters | Co-star |
| The Wraith | Keri Johnson | Mike Marvin | Starring |
| 1987 | Zombie High | Suzi | Ron Link | Co-star |
| 21 Jump Street (TV series) (1.9 Blindsided) | Diane Nelson | David Jackson | Guest appearance |
| 1988 | Two Moon Junction | April Delongpre | Zalman King | Starring |
| 1990 | Meridian: Kiss Of The Beast | Catherine Bomarzini | Charles Band | Starring |
| 1990-1991 | Twin Peaks (TV series) | Audrey Horne | David Lynch, Mark Frost | Series regular |
| 1990 | Wild at Heart | Girl in accident | David Lynch | Co-star |
| 1991 | Dillinger (TV) | Evelyn "Billie" Frechette | Rupert Wainwright | Starring |
| 1992 | Desire and Hell at Sunset Motel | Bridget "Bridey" DeSoto | Alien Castle | Starring |
| Diary of a Hitman | Jain Zidzyck | Roy London | Starring |
| Ruby | Sheryl Ann "Candy Cane" DuJean | John Mackenzie | Starring / also song performer ("Blues in the Night" and "It Had to be You") |
| Of Mice and Men | Curley's wife | Gary Sinise | Starring |
| 1993 | Three of Hearts | Ellen Armstrong | Yurek Bogayevicz | Starring |
| Boxing Helena | Helena | Jennifer Chambers Lynch | Starring |
| Fatal Instinct | Laura Lincolnberry | Carl Reiner | Starring |
| 1994 | Spring Awakening (TV) | Margie | Jack Gold | Starring |
| 1995 | Slave of Dreams (TV) | Zulaikha | Robert M. Young | Starring |
| Tales from the Crypt (TV series) (6.15 You, Murderer) | Erika | Robert Zemeckis | Starring |
| Liz: The Elizabeth Taylor Story (TV) | Elizabeth Taylor | Kevin Connor | Starring |
| 1996 | A Season in Purgatory (TV) | Kit Bradley | David Greene | Starring |
| Lovelife | Molly | Jon Harmon Feldman | Starring |
| 1997 | Just Write | Amanda Clark | Andrew Gallerani | Starring |
| Friends (TV series) (3.14 The One with Phoebe's Ex-Partner) | Ginger | Robby Benson | Guest appearance |
| Hungry for Survival (renamed as Prey) (TV series) (unaired pilot) | Dr. Sloan Larkin | | Lead (replaced by Debra Messing) |
| 1998 | Nightmare Street (TV) | Joanna Burke/Sarah Randolph | Colin Bucksey | Starring |
| Darkness Falls | Sally Driscoll | Gerry Lively | Starring |
| Cupid (TV series) (1.7 Pick-Up Schticks) | Helen Davis | Tucker Gates | Guest appearance |
| 1998-2001 | Rude Awakening (TV series) | Billie Frank | Claudia Lonow | Lead |
| 1999 | Cement | Lyndel "Lyn" Holt | Adrian Pasdar | Starring |
| 2001 | Off Season (TV) | Patty Winslow | Bruce Davison | Starring / also song performer ("It's Always You") |
| The Outer Limits (TV series) (7.7 Replica) | Nora Griffiths | Brad Turner | Starring |
| Night Visions (1.8 Used Car[1]) | Charlotte | Michael W. Watkins | Starring |
| 2002 | Birds of Prey (TV series) (unaired pilot) | Dr. Harleen Quinzel/Harley Quinn | Brian Robbins | Co-star (replaced by Mia Sara) |
| Swindle | Sophie Zenn | K.C. Bascombe | Starring |
| Watching Ellie (TV series) (1.5 Cheetos,[2] 1.7 Gift[3]) | Vanessa | Brad Hall | Guest appearance (2 episodes) |
| Dawson's Creek (TV series) (5.20 Separate Ways (Worlds Apart), 5.21 After Hours, 5.22 The Abby) | Alexandra "Alex" Pearl | Kevin Williamson | Guest appearance (3 episodes) |
| Law & Order: Special Victims Unit (TV series) (4.2 Deception) | Gloria Stanfield | Constantine Makris | Guest appearance |
| 2003 | The United States of Leland | Angela Calderon | Matthew Ryan Hoge | Co-star |
| Gilmore Girls (TV series) (3.21 Here Comes the Son) | Sasha | Amy Sherman-Palladino | Guest appearance |
| 2003-2004 | Boston Public (TV series) | Violet Montgomery | David E. Kelley | Recurring role (season 4) |
| 2004 | Mister Ed (TV series) (unaired pilot) | Carlotta Pope | Michael Spiller | Starring |
| Cavedweller (TV) | M.T. | Lisa Cholodenko | Co-star |
| NCIS (TV series) (1.10 Left for Dead) | Jane Doe/Suzzanne McNeil | James Whitmore Jr. | Guest appearance |
| 2005 | Lesser of Three Evils[4] | Katie | Wayne Kennedy | Starring |
| Judging Amy (TV series) (6.22 My Name Is Amy Gray...[5]) | Heather Reid | Helen Shaver | Guest appearance |
| The 4400 (TV series) (2.7 Carrier) | Jean DeLynn Baker | Leslie Libman | Guest appearance |
| 2006 | Whitepaddy | Karen Greenly | Geretta Geretta | Starring |
| Novel Romance | Liza Normane | Emily Skopov | Co-star |
| Presumed Dead (TV) | Detective Mary Anne "Coop" Cooper | George Mendeluk | Starring |
| Three Moons Over Milford (TV series) (unaired pilot) | Janet Davis | Howard Chesley, Jon Boorstin | Lead (replaced by Elisabeth McGovern) |
| CSI: Miami (TV series) (4.22 Open Water) | Gwen Creighton | Scott Lautanen | Guest appearance |
| Smith (TV series) (1.6 Six) | Debbie Turkenson | Alex Zakrzewski | Guest appearance |
| 2006-2007 | Gilmore Girls (TV series) | Anna Nardini | Amy Sherman-Palladino | Recurring role (seasons 6-7) |
| 2007 | The Dukes of Hazzard: The Beginning | Lulu Hogg | Robert Berlinger | Co-star |
