SDHC

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SDHC
Pengidentifikasi
Alias	SDHC, CYB560, CYBL, PGL3, QPS1, SDH3, succinate dehydrogenase complex subunit C
ID Eksternal	OMIM: 602413; MGI: 1913302; HomoloGene: 2256; GeneCards: SDHC; OMA:SDHC - orthologs
Lokasi gen (Manusia) Kr. Kromosom 1 (manusia)[1] Pita 1q23.3 Awal 161,314,381 pb[1] Akhir 161,363,206 pb[1]
Pola ekspresi RNA Bgee Manusia Tikus (ortologi) Ekspresi tertinggi di Pulau Langerhans right adrenal cortex human kidney left adrenal gland left adrenal cortex rektum otot polos Usus dua belas jari left ventricle right lobe of liver Ekspresi tertinggi di soleus muscle interventricular septum plantaris muscle Atrium (anatomi) muscle of thigh myocardium of ventricle digastric muscle Otot sternokleidomastoid extensor digitorum longus muscle Otot temporalis Referensi data ekspresi selengkapnya BioGPS n/a
Ontologi gen Fungsi molekuler electron transfer activity oxidoreductase activity, acting on the CH-CH group of donors succinate dehydrogenase activity heme binding metal ion binding succinate dehydrogenase (ubiquinone) activity ubiquinone binding Komponen seluler komponen integral membran mitochondrial inner membrane respiratory chain complex II succinate dehydrogenase complex mitokondria membran mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) Proses biologis aerobic dissimilation Siklus asam sitrat mitochondrial electron transport, succinate to ubiquinone response to oxidative stress Sumber:Amigo / QuickGO
Ortologi Spesies Manusia Tikus Entrez 6391 66052 Ensembl ENSG00000143252 ENSMUSG00000058076 UniProt Q99643 Q9CZB0 RefSeq (mRNA) NM_001035511 NM_001035512 NM_001035513 NM_001278172 NM_003001 NM_025321 RefSeq (protein) NP_001030588 NP_001030589 NP_001030590 NP_001265101 NP_002992 NP_079597 Location (UCSC) Chr 1: 161.31 – 161.36 Mb n/a PubMed search [2] [3]
Wikidata
Lihat/Sunting Manusia Lihat/Sunting Tikus

SDHC merupakan berkas genetik pada kromosom 1 lokasi 1q23.3 dengan ekspresi genetik berupa protein cybL yang merupakan sub-unit C dari suksinat dehidrogenase. Mutasi pada gen ini mengakibatkan paraganglioma.^[4]

Rujukan

1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000143252 – Ensembl, May 2017
2. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. ↑ (Inggris) "SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa [ Homo sapiens ]". Entrez Gene. Diakses tanggal 2010-11-05.

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